Our Science

Our Science

We didn't stop at the active ingredient. We engineered the entire journey.

The Regenerative Power of PDRN

The gold standard in skin regeneration.

PDRN (Polydeoxyribonucleotide) is a naturally derived ingredient with a research history spanning more than three decades. Studied extensively in clinical and aesthetic dermatology, it works by supporting the skin's natural renewal processes at a cellular level - associated with visible improvements in the appearance of firmness, texture, fine lines, and overall skin quality.

What sets PDRN apart is its mechanism. Rather than working at the surface, it is formulated to support the biological processes that happen beneath it, including the activity of fibroblasts, the cells responsible for collagen and elastin. The result is regeneration that works with the skin, not against it.

Gentle enough for the most sensitive skin. Effective enough to be the foundation of every BRG formula.

LSME10™ Liposomal Delivery Technology

LSME10™ Liposomal Delivery Technology

Efficacy begins with delivery.

A high-concentration active is only as effective as its ability to reach the skin. LSME10™ is our proprietary liposomal encapsulation system designed to carry PDRN past the skin's outer barrier and into the deeper layers where visible renewal begins.

The liposomal carrier protects the active from degradation on the skin's surface, releasing it gradually for a prolonged period of time. The difference between a formula that performs and one that doesn't is often invisible. With LSME10™, it is engineered.

The Rosé Regeneration Signature

The Rosé Regeneration Signature

Regeneration deserves protection.

As skin actively renews, it benefits from antioxidant support. Environmental stressors including UV exposure, pollution and oxidative stress can interfere with the skin's natural regenerative activity.

Rosé Protection is formulated to address exactly this.

Built around two botanically derived actives with peer-reviewed credentials - Eclipta Prostrata, shown to have potent antioxidant and UVB protective properties, and Coccinia Indica Fruit Extract documented for its anti-inflammatory and skin conditioning activity. 

Rosé Protection provides the antioxidant shield that allows the full regenerative cycle to complete. 

The rosé hue is not cosmetic. It is a natural expression of botanical extract concentration. 

Visible evidence of antioxidant protection.

(Chan et al. Scientific World Journal, 2014; Harad & Game, International Journal of Pharmaceutical Research, 2023)

Clinical-level formulation standards

Clinical-level formulation standards

Luxury skincare, engineered with medical discipline.

Every BRG Skin formula is developed to the standard we believe luxury skincare should always have met - dermatologist-reviewed, stability tested, pH balanced, and formulated at concentrations chosen for efficacy, not aesthetics.

We don't dilute science. We elevate it.
What's Inside

Key Actives
Clinically Studied Active

PDRN

Studied in clinical and aesthetic dermatology for over three decades. Supports visible skin renewal, texture refinement, and overall skin quality.

Botanical Actives

Rosé Protection Complex

Eclipta Prostrata and Coccinia Indica, botanically derived actives with documented antioxidant, anti-inflammatory, and UVB protective properties. The science behind the signature hue.

Barrier Support

Ceramide Complex

Three skin-identical ceramides, NP, AP, and EOP, that replenish the lipids naturally found in healthy skin. Where regeneration renews, ceramides restore. Reinforcing the barrier, sealing in moisture, and defending against environmental stress for skin that feels resilient and protected.

Our Clinical Philosophy

Our Clinical Philosophy

Regeneration requires both potency and precision.

Our approach is guided by three principles:
Regeneration Active First: Ingredients with established research lead every formula.
Delivery Determines Results: LSME10™ is designed to optimize absorption and performance. Most PDRN products stop at the skin's surface. LSME10™ is designed to go further — carrying pharmaceutical-grade PDRN deeper into the skin where visible renewal begins, and releasing it gradually so regeneration continues long after application.
Luxury Through Science: Sensory elegance grounded in measurable results.

Tested. Proven. Trusted.

Tested. Proven. Trusted.

90% saw visible improvement within 3 weeks.

In an independent consumer perception study, participants using the Rosé Regeneration Emulsion reported visible improvements across key skin concerns.

After 8 weeks:

  • 90% reported smoother, more refined-looking skin
  • 80% reported firmer, more resilient-looking skin
  • 80% experienced zero irritation

*Based on an independent consumer perception pilot study (n=10). Results based on self-assessment. Results may vary.

The Science, Applied

The Science, Applied

The BRG 3‑Step Regenerative System
Step 1: Serum - Illuminate Hydrates, brightens, and prepares skin for what follows. The first layer of the regenerative ritual.
Step 2: Emulsion - Regenerate The hero formula. Pharmaceutical-grade PDRN delivered through LSME10™ for visible renewal over time.
Step 3: Cream - Protect & Perfect Seals in moisture, supports barrier function, and amplifies the luminosity that regeneration reveals.

Three steps. One complete journey.